反应详情

The same compound is obtained when a solution of 1.1 g. dicyclohexylcarbodiimide in 5 ml. diethyl ether is added at 0° C. to a mixture of 0.97 g. p-ethoxycarbonylbenzoic acid and 0.34 g. 2-cyanoaziridine in 15 ml. diethyl ether, stirred for 2 hours at this temperature and then for 1 hour at ambient temperature, the precipitated dicyclohexylurea is filtered off with suction (1.13 g.), the filtrate evaporated and the evaporation residue is triturated with about 3 ml. diethyl ether. The yield is 0.66 g.; m.p. 92°-94° C.

1. customThe same compound is obtained when a solution of 1.1 g
2. filtrationthe precipitated dicyclohexylurea is filtered off with suction (1.13 g.)
3. customthe filtrate evaporated
4. customthe evaporation residue is triturated with about 3 ml