Quinoline → HCID 15572315, compound

Participants

Reaction Steps

A solution of 3.6 g (0.01 mole) of 2-allylthio-4,5-bis(4-chlorophenyl)pyrrole in 20 ml acetic anhydride was added dropwise to 20 ml quinoline preheated at 170°. The mixture was kept at 170° an additional 45 minutes, then cooled. Most of the acetic acid, acetic anhydride and quinoline were removed by distillation under reduced pressure. The residue was chromatographed on 125 g of Silic AR CC-7, eluting with toluene, to give, after recrystallization from hexane/methyl cyclohexane, 2.7 g of white product, m.p. 131°-2°.

Provenance & Evidence