HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 5-Hydroxypyrazine-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 5-Chloropyrazinoic acid | HCID 465472 | — |
| Product | 5-Hydroxypyrazine-2-carboxylic acid | HCID 178524774 | — |
Reaction Steps
For example the compound 2-carboxy-5-chloro-pyrazine can be prepared by treating with an excess of phosphorus oxychloride, at the reflux temperature, the 2-carboxy-5-hydroxy-pyrazine compound in its turn obtained in the manner described in Helv. Chim. Acta 47, 873 (1964).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04267327 |
| Source dataset | uspto-grants-1981_05 |
| ORD ID | ord-5e7efc6280ef4d27ad174e1cc18a14da |
| Source note | uspto-grants-1981_05 |