Oxazoline → HCID 54185869, compound

HRID 2286750Notes

Reaction equation

[F:1][C:2]([F:22])([F:21])[C:3]1[CH:4]=[C:5]([CH:9]([NH:14][C:15]([NH:17][CH2:18][CH2:19]Cl)=[O:16])[C:10]([F:13])([F:12])[F:11])[CH:6]=[CH:7][CH:8]=1.O1CCN=C1>>[F:11][C:10]([F:13])([F:12])[CH:9]([NH:14][C:15]1[O:16][CH2:19][CH2:18][N:17]=1)[C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([C:2]([F:22])([F:21])[F:1])[CH:4]=1

Participants

Reactant 2

HCID 68157Oxazoline

HCID 54204570HCID 54204570, compound

Product 1

HCID 54185869HCID 54185869, compound

Procedure

Using the same procedure as in example III step B and starting from N-[α-(3-trifluoromethyl phenyl) trifluoroethyl] N'-(β-chloroethyl) Urea, dl 2-[α-(trifluoromethyl) 3-trifluoromethyl benzylamino)] oxazoline is produced. It melts at 129°-132°.

Workup

customis produced

Sources & evidence

ORD record: ord-1e2fb09d45f943adb64f798f5ace621e
Source dataset: uspto-grants-1981_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04267345

Reaction notes

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