Pyridine → HCID 23460501, compound

HRID 2286877Notes

Reaction equation

HRID 2286877 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([CH3:12])[C:6]1[C:13](O[C:16](=[O:17])[C:5]2=1)=[O:14].[N:18]1C=CC=C[CH:19]=1>>[O:17]=[C:16]1[C:5]2[C:4]3[CH:3]=[C:2]([Br:1])[CH:11]=[CH:10][C:9]=3[N:8]=[C:7]([CH3:12])[C:6]=2[C:13](=[O:14])[N:18]1[CH3:19]

Participants

3

Reactant 2

HCID 1049PyridineHCID 15154343HCID 15154343, compound

Product 1

HCID 23460501HCID 23460501, compound

Procedure

To 350 ml of dry pyridine was added 14.7 g of the anhydride (ix) in a 3neck flask with reflux condenser, drying tube, magnetic stirrer and a thermometer. The flask was cooled with an ice/H2O bath and dry reagent grade CH3NH2 was passed into the mixture. The flask was then allowed to warm up to room temperature and refluxed for 20 hours.

Workup

  1. temperaturewith reflux condenser
  2. customdrying tube, magnetic stirrer
  3. temperatureThe flask was cooled with an ice/H2O bath
  4. temperaturerefluxed for 20 hours

Sources & evidence

ORD record
ord-d84472cfd252422f8a94ec859c284a4e
Source dataset
uspto-grants-1981_05
Patent number
US04268513

Reaction notes

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