Thionyl Chloride → 7-Dimethylsulfamoyl-1,4-benzodioxane-5-carbonyl chloride

HRID 2286927Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 2286927
S(Cl)([Cl:3])=O.[CH3:5][N:6]([CH3:23])[S:7]([C:10]1[CH:11]=[C:12]([C:20](O)=[O:21])[C:13]2[O:18][CH2:17][CH2:16][O:15][C:14]=2[CH:19]=1)(=[O:9])=[O:8]>>[CH3:5][N:6]([CH3:23])[S:7]([C:10]1[CH:11]=[C:12]([C:20]([Cl:3])=[O:21])[C:13]2[O:18][CH2:17][CH2:16][O:15][C:14]=2[CH:19]=1)(=[O:9])=[O:8]

Komponenten

3

Edukt 2

HCID 24386Thionyl ChlorideHCID 64553187-(N,N-dimethylsulphamoyl)-2,3-dihydro-1,4-benzodioxin-5-carboxylic acid

Produkt 1

HCID 205447057-Dimethylsulfamoyl-1,4-benzodioxane-5-carbonyl chlorideAusbeute 100,1 %

Versuchsvorschrift

190 g of thionyl chloride and 153 g of 7-dimethylsulfamoyl-1,4-benzodioxane-5-carboxylic acid were introduced into a balloon flask provided with a condenser. The mixture was heated and then the excess thionyl chloride was distilled off. 163 g of 7-dimethylsulfamoyl-1,4-benzodioxane-5-carbonyl chloride were obtained (M.P.: 160°-162° C.; yield: 100%).

Aufarbeitung

  1. customprovided with a condenser
  2. temperatureThe mixture was heated
  3. distillationthe excess thionyl chloride was distilled off

Quellen und Nachweise

ORD-Eintrag
ord-0460a4987ace4cbf831dec8a4359eb03
Quelldatensatz
uspto-grants-1981_05
Patentnummer
US04268512

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