HCID 54522606, compound → HCID 23460560, compound

Participants

Reaction Steps

A solution of 42 g of N-(4-chloro-3-nitrobenzoyl)N-n-hexadecyl-2-nitro-aniline in 700 ml of ethanol is allowed to run rapidly into a mixture, which has been heated to 60° C., of 89 g of iron powder in 120 ml of water and 40 ml of concentrated hydrochloric acid, with vigorous stirring. The reaction mixture is then stirred for four hours at the reflux temperature. A further 100 ml of concentrated hydrochloric acid and 200 ml of ethanol are then added and the mixture is filtered hot. About 400 ml of ethanol are then distilled off and the residue is left to crystallise out at 4° C. After filtering and drying, 32 g of the compound are obtained in the form of the hydrochloride with a melting point of 162° to 163° C.

Provenance & Evidence