Hydroxyamine hydrochloride → HCID 12876704, compound

Participants

Reaction Steps

3,5-Diethyl-4-[(4-methoxyphenyl)methyl]isoxazole [I; Ar is 4-CH3OC6H4, Y is CH2, R is C2H5 ] was prepared from 41.1 g. of 4-(4-methoxyphenylmethyl)-3,5-heptanedione and 12.0 g. of hydroxylamine hydrochloride in 100 ml. of pyridine according to the procedure of Example 2, part (b), and was obtained in the form of a colorless oil, b.p. 145°-146° C. (0.1 mm.); MIC=25 μg/ml (herpes 2).

Provenance & Evidence