Pyridine → HCID 21764419, compound

Participants

Reaction Steps

18.6 g. of methanesulfonyl chloride are added dropwise while stirring and cooling with ice to a solution of 27 g. of 1-phenyl-2,5-cyclohexadien-1-ethanol in 270 ml. of absolute pyridine. After stirring at room temperature for 3 hours, about 250 ml. of water are added. The separated product is filtered off under suction, washed with water and dried. The crude product is recrystallized from benzene/hexane, there being obtained methansulfonic acid 2-(1-phenyl-2,5-cyclohexadien-1-yl)-ethyl ester as colorless crystals of melting point 64°-65° C.

Provenance & Evidence