Diethyl Ether → HCID 23459452, compound

Participants

Reaction Steps

0.76 g. of lithium aluminum hydride is placed in 20 ml. of absolute ether. 2.42 g. of methyl 2-(1-phenyl-2,5-cyclohexadien-1-yl)-propionate in 20 ml. of absolute ether are added dropwise thereto. After stirring at room temperature for 5 hours, the mixture is worked-up as follows: The mixture is treated with ethyl acetate and water, filtered under suction and the organic phase is separated from the aqueous phase. The organic phase is dried with sodium sulfate, filtered and evaporated. The crude product obtained is chromatographed on 80 g. of silica gel with ether/petroleum ether (1:2), oily β-methyl-1-phenyl-2,5-cyclohexadien-1ethanol being obtained.

Provenance & Evidence