Benzoyl chloride → HCID 23459594, compound

HRID 2287148Notes

Reaction equation

HRID 2287148 reaction equation
[C:1]1([N:7]2[C:12](=[O:13])[C:11]3[CH:14]=[N:15][C:16]4[NH:20][N:19]=[CH:18][C:17]=4[C:10]=3[N:9]3[N:21]=[CH:22][N:23]=[C:8]23)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:24](Cl)(=[O:31])[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>N1C=CC=CC=1>[C:24]([N:20]1[C:16]2[N:15]=[CH:14][C:11]3[C:12](=[O:13])[N:7]([C:1]4[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=4)[C:8]4[N:9]([N:21]=[CH:22][N:23]=4)[C:10]=3[C:17]=2[CH:18]=[N:19]1)(=[O:31])[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1

Participants

4

Reactant 2

HCID 7412Benzoyl chlorideHCID 23459607HCID 23459607, compound

Product 1

HCID 23459594HCID 23459594, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

0.01 mol. of 4-phenyl-4H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidin-5(8H)-one and 0.02 mol. of benzoyl chloride are stirred overnight in 50 ml. of dry pyridine at room temperature. On addition of 50 ml. of water, 8-benzoyl-4-phenyl-4H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]-triazolo[1,5-a]pyrimidin-5(8H)-one is filtered off.

Workup

  1. customat room temperature
  2. additionOn addition of 50 ml
  3. filtrationof water, 8-benzoyl-4-phenyl-4H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]-triazolo[1,5-a]pyrimidin-5(8H)-one is filtered off

Sources & evidence

ORD record
ord-b376899da9ff4cccbaf9fa863d3a9c30
Source dataset
uspto-grants-1981_05
Patent number
US04269836

Reaction notes

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