HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloromethyl methyl sulfide → 4-methylthiomethyl-4H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]-triazolo[1,5-a]pyrimidin-5(8H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloromethyl methyl sulfide | HCID 16916 | — |
| Reactant | 3-Chloro-N,N-dimethyl-1-propanamine | HCID 66960 | — |
| Reactant | 4-Methyl-4H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidin-5(8H)-one | HCID 23459593 | — |
| Reactant | 8-Ethyl-4H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]-triazolo[1,5-a]pyrimidin-5(8H)-one | HCID 135593852 | — |
| Product | 4-methylthiomethyl-4H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]-triazolo[1,5-a]pyrimidin-5(8H)-one | HCID 23459638 | — |
Reaction Steps
By substituting methylthiomethyl chloride for the 3-(dimethylamino)propyl chloride in the procedure of Example 2 and substituting the 4H-pyrazolo[1,5-a]pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidin-5(8H)-one obtained in Example 11 for the 8-ethyl-4H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidin-5(8H)-one, 4-methylthiomethyl-4H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]-triazolo[1,5-a]pyrimidin-5(8H)-one is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04269836 |
| Source dataset | uspto-grants-1981_05 |
| ORD ID | ord-fd7b7addbda34b93ac0e1d77b287a8b4 |
| Source note | uspto-grants-1981_05 |