HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 3-Acetyl-5-(1,3-benzoxazol-2-yl)-1,3,4-oxadiazol-2(3H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 5-(1,3-Benzoxazol-2-yl)-1,3,4-oxadiazol-2-ol | HCID 132876 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 3-Acetyl-5-(1,3-benzoxazol-2-yl)-1,3,4-oxadiazol-2(3H)-one | HCID 13094302 | — |
Reaction Steps
5.0 g of 2-(2-oxo-3H-1,3,4-oxadiazole-5-yl)benzoxazole in 50 ml of acetic acid containing 5 ml of acetic anhydride was heated for 1 hour at 100°. The mixture was poured into water and the crystalline product filtered. Recrystallization from acetonitrile gave mp. of 231°-232°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04269846 |
| Source dataset | uspto-grants-1981_05 |
| ORD ID | ord-9e930962992a4f61b6499fb8d0ee0fd9 |
| Source note | uspto-grants-1981_05 |