2-Amino-6-methoxybenzothiazole → 2-Amino-6-benzothiazolol

Participants

Reaction Conditions

Reaction Steps

1800 g of 2-amino-6-methoxy-benzothiazole were dissolved in 6 l of a 48% by weight aqueous hydrobromic acid and refluxed. The obtained reaction product was cooled over night and the precipitate was removed by suction filtering. The filtrate was brought at pH 6 with a 30% by weight aqueous hydroxide solution and cooled to 20° C. The obtained precipitate was separated by suction filtering, washed with water and dried at 30° C. Melting point: 257° C. (sublimation).

Provenance & Evidence