Benzaldehyde → HCID 19261677, compound

Participants

Reaction Conditions

Reaction Steps

A stirring solution of 65 g (0.75 mole) of 2-imidazolidinone in 2000 ml of 2 N H2SO4 is cooled to SAC. A 53 g (0.77 mole) portion of NaNO2 is added portionwise, over a 15 minute period, maintaining the temperature at 0° C. The resulting mixture is stirred at 0° C. for 2 hours. A 108 g (1.65 mole) portion of zinc dust is added portionwise, over a 1 hour period, maintaining the temperature at 0° C. The reaction is stirred at 0° C. for 0.5 hour and then at ambient temperature for 1 hour. The excess zinc is removed by filtration. The filtrate is treated all at once, with a solution of 80 g (0.75 mole) of benzaldehyde, in 400 ml of S.D.A. #32 and the resulting mixture is stirred for 16 to 18 hours at ambient temperature. The solid is collected by filtration, washed with H2O, and air-dried to yield 124 g (87%) of 1-[(phenylmethylene)amino]-2-imidazolidinone.

Provenance & Evidence