HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2287416Generated: October 31, 2026
Potassium Carbonate → HCID 22645641, compound
https://huagongshe.com/reaction/2287416
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Benzene, 1,3-dichloro-2-fluoro-5-(trifluoromethyl)- | HCID 157026 | — |
| Reactant | 6-Fluoroindole | HCID 351278 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22645641 | HCID 22645641 | — |
Reaction Steps
To a solution of 3,5-dichloro-4-fluorobenzotrifluoride (34.5 g) in dimethylformamide (250 ml) was added 6-fluoroindole (34.5 g) and potassium carbonate (20.4 g). The mixture was heated at 90° C. for 6 hours and then left to stir for 16 hours at room temperature. The reaction was diluted with water (1000 ml) and extracted with hexane (1000 ml). The organic fraction was separated and evaporated to dryness to give the title compound as a colourless liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06083965 |
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| Source dataset | uspto-grants-2000_07 |
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| ORD ID | ord-9a74a4b231eb4526804e103e4314e35b |
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| Source note | uspto-grants-2000_07 |
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