HCID 85452192, compound → HCID 15485311, compound

HRID 2287452Notes

Reaction equation

HRID 2287452 reaction equation
[C:1]([C:5]1[CH:6]=[C:7]([C:15]([CH2:25][CH2:26][CH3:27])=[CH:16][CH:17]=[CH:18][C:19]([CH3:24])=[CH:20][C:21]([O-:23])=[O:22])[CH:8]=[C:9]([C:11]([CH3:14])([CH3:13])[CH3:12])[CH:10]=1)([CH3:4])([CH3:3])[CH3:2]>CO>[C:1]([C:5]1[CH:6]=[C:7](/[C:15](/[CH2:25][CH2:26][CH3:27])=[CH:16]\[CH:17]=[CH:18]\[C:19](\[CH3:24])=[CH:20]\[C:21]([OH:23])=[O:22])[CH:8]=[C:9]([C:11]([CH3:12])([CH3:13])[CH3:14])[CH:10]=1)([CH3:2])([CH3:3])[CH3:4]

Participants

3

Reactant 1

HCID 85452192HCID 85452192, compound

Product 1

HCID 15485311HCID 15485311, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Compound 28 was prepared in the same manner as 27 except that the cis isomer 26 was used instead of 25: TLC (10% MeOH-90% CHCl3) Rf 0.8; mp 166-169° C.; 1H-NMR (CDCl3)δ 0.89 (t, J=7 Hz, 3H, CH2CH3), 1.31 (s, 9H, CH3), 1.32 (s, 9H, CH3), 1.42 (m, 2H, CH2CH2CH3), 2.15 (s, 3H, CH3), 2.49 (t, J=7 Hz, 2H, CH2CH2CH3), 5.76 (s, 1H, =CH), 6.23 (d, J=11 Hz, 1H, =CH), 6.28 (d, J=15 Hz, 1H, =CH), 6.78 (dd, J=15 Hz, 1H, =CH), 7.04 (s, 2H, Ar--H), 7.35 (s, 1H, Ar--H).

Sources & evidence

ORD record
ord-41fdf1a539664f28bbd48243d6ce8c2e
Source dataset
uspto-grants-2000_07
Patent number
US06083977

Reaction notes

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