反应详情

A solution of 54.05 g of the crude 1-allyl-2-ethylbenzene in 500 mL of 1:1 CH2Cl2 --CH3OH was cooled to -78° C. A stream of O3 was bubbled through the solution for 3 h, until all of the starting material had disappeared. Then a stream of air was bubbled through the solution until the blue color had faded. A total of 25 mL of methyl sulfide was added and the solution was stirred at room temperature for 1 h. The solution was concentrated and dried under vacuum to afford (2-ethylphenyl) acetaldehyde as a colorless oil which was used directly in the next step.

1. customA stream of O3 was bubbled through the solution for 3 h
2. customThen a stream of air was bubbled through the solution until the blue color
3. additionA total of 25 mL of methyl sulfide was added
4. concentrationThe solution was concentrated
5. customdried under vacuum