Water → (2,6-Dimethyl-3-nitrophenyl)methanol

HRID 2287566Notes

Reaction equation

HRID 2287566 reaction equation
C([O:4][CH2:5][C:6]1[C:11]([CH3:12])=[CH:10][CH:9]=[C:8]([N+:13]([O-:15])=[O:14])[C:7]=1[CH3:16])(=O)C.[OH-].[Na+].O>CO>[CH3:16][C:7]1[C:8]([N+:13]([O-:15])=[O:14])=[CH:9][CH:10]=[C:11]([CH3:12])[C:6]=1[CH2:5][OH:4]

Participants

5

Reactant 3

HCID 962WaterHCID 14798Sodium HydroxideHCID 10537042(2,6-Dimethyl-3-nitrophenyl)methyl acetate

Product 1

HCID 10487641(2,6-Dimethyl-3-nitrophenyl)methanolYield 82.4%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 2,6-dimethyl-3-nitrobenzyl acetate (26.9 g) in methanol (266 ml) was added 1N sodium hydroxide solution (133 ml) at ambient temperature, and the mixture was stirred for 30 minutes. To the reaction mixture was added water, and the resulting precipitates were collected by filtration to give 2,6-dimethyl-3-nitrobenzyl alcohol (18.0 g) as pale yellow crystals.

Workup

  1. customthe resulting precipitates
  2. filtrationwere collected by filtration

Sources & evidence

ORD record
ord-5061872deed6409f82b2f2ebbdec7680
Source dataset
uspto-grants-2000_07
Patent number
US06083961

Reaction notes

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