N-Methylformamide → HCID 18705902, compound

Participants

Reaction Steps

Using procedure 41, methyl 2-(dipropylamino)-6-ethoxy-2,3-dihydro-1H-indene-5-carboxylate (77, 0.32 g, 1 mmol) was treated with N-methylformamide (0.58 mL, 10 mmol). Chromatographic purification yielded pure product 83 as a oil which was converted into the HCl salt and crystallized from EtOAc/MeOH to give a white solid (m.p. 156-159° C.).

Provenance & Evidence