Hydrochloric Acid → HCID 18705894, compound

Participants

Reaction Steps

Using procedure 48, 6-(dipropylamino)-6,7-dihydrocyclopent[f]isoindole-1,3(2H,5H)-dione (93, 0.14 g, 0.5 mmol) was treated with 1-(chloromethyl)-1H-benzotriazole (0.08 g, 0.5 mmol). Purification using silica gel, eluting with 3:1 hexane/acetone, afforded a solid that was converted to an HCl salt and recrystallized from hot MeOH/EtOAc to give 98 as a white solid (m.p. 254-256° C.).

Provenance & Evidence