Hydrochloric Acid → HCID 18705877, compound

Participants

Reaction Steps

Using procedure 48, 6-(dipropylamino)-6,7-dihydrocyclopent[f]isoindole-1,3(2H,5H)-dione (93, 0.14 g, 0.5 mmol) was treated with 3-(chloromethyl)-1,2,4-oxadiazole (0.09 g, 0.75 mmol). Purification using silica gel, eluting with 7:1 CH2Cl2 /acetone, afforded a solid that was converted to an HCl salt and recrystallized from CH2Cl2 /Et2O to give 100 as a white solid (m.p. 190-191° C.).

Provenance & Evidence