Hydrochloric Acid → HCID 18705819, compound

Participants

Reaction Steps

Using procedure 49, 2-(dipropylamino)-2,3-dihydro-1H-indene-5,6-dicarboxylate (92, 0.35 g, 1.0 mmol) was treated with 3-aminomethylpyridine (0.14 mL, 1.4 mmol). Purification using silica gel, eluting with 19:1 CH2Cl2 /MeOH sat'd with NH3, afforded an oil that was converted to an HCl salt and recrystallized from hot MeOH/EtOAc to give 116 as a white solid (m.p. 141-146° C.).

Provenance & Evidence