Hydrochloric Acid → HCID 18705906, compound

Participants

Reaction Steps

Using procedure 47, the 6-(dipropylamino)-6,7-dihydro-2-methylcyclopent[f]isoindole-1,3(2H,5H)-dione (120, 0.13 g, 0.4 mmol) was reduced with Zinc dust (0.26 g, 4.0 mmol) in glacial HOAc (10 mL). Purification via crystallization from EtOAc/MeOH gave an off-white solid that was converted to an HCl salt and recrystallized from EtOAc/MeOH to give 126 as a white solid (m.p. 242-243° C.).

Provenance & Evidence