Hydrochloric Acid → HCID 18705864, compound

Participants

Reaction Steps

Using procedure 47, 6-(dipropylamino)-6,7-dihydro-2-phenylcyclopent[f]isoindole-1,3(2H,5H)-dione (121, 0.09 g, 0.23 mmol) was reduced with Zinc dust (0.15 g, 2.3 mmol) in glacial HOAc (5 mL). Purification on silica gel, eluting with 3:1 hexane/acetone gave an oil that was converted to an HCl salt and recrystallized from EtOAc/MeOH to give 127 as a white solid (m.p. 248-249° C.).

Provenance & Evidence