Potassium Hydroxide → HCID 18702922, compound

HRID 2287943Notes

Reaction equation

HRID 2287943 reaction equation
[CH:1]([N:4]([CH:22]([CH3:24])[CH3:23])[CH2:5][CH2:6][O:7][C:8]1[CH:9]=[C:10]2[C:15](=[CH:16][CH:17]=1)[CH:14]=[C:13]([C:18]([O:20]C)=[O:19])[CH:12]=[CH:11]2)([CH3:3])[CH3:2].[OH-].[K+]>CO>[CH:22]([N:4]([CH:1]([CH3:3])[CH3:2])[CH2:5][CH2:6][O:7][C:8]1[CH:9]=[C:10]2[C:15](=[CH:16][CH:17]=1)[CH:14]=[C:13]([C:18]([OH:20])=[O:19])[CH:12]=[CH:11]2)([CH3:23])[CH3:24]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 18702919HCID 18702919, compound

Product 1

HCID 18702922HCID 18702922, compoundYield 95.7%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

3.6 g of methyl 6-(2-diisopropylaminoethoxy)-2-naphthoate and 1.8 g of KOH are heated under reflux for 5 h in methanol. After concentrating and taking up the residue in water, the mixture is adjusted to pH 6 using hydrochloric acid, whereupon the product precipitates. 3.3 g of 6-(2-diisopropylaminoethoxy)-2-naphthoic acid are obtained;

Workup

  1. concentrationAfter concentrating
  2. customwhereupon the product precipitates

Sources & evidence

ORD record
ord-d036e9f8c8be4b22b23ddbf22bef59ce
Source dataset
uspto-grants-2000_07
Patent number
US06087304

Reaction notes

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