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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 228796Generated: October 25, 2026

(4,5-Dimethylfuran-2-yl)-(4,5-dimethylthiazol-2-yl)methanol → (4,5-Dimethylfuran-2-yl)(4,5-dimethylthiazol-2-yl)-methanone

https://huagongshe.com/reaction/228796

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4,5-Dimethylfuran-2-yl)-(4,5-dimethylthiazol-2-yl)methanolHCID 23078354—
CatalystHCID 178418406HCID 178418406—
SolventChloroformHCID 6212—
Product(4,5-Dimethylfuran-2-yl)(4,5-dimethylthiazol-2-yl)-methanoneHCID 2307824797.1%

Reaction Steps

(4,5-Dimethylfuran-2-yl)-(4,5-dimethylthiazol-2-yl)methanol (945 mg) was dissolved in chloroform (20 ml) to prepare a solution. Manganese dioxide (3.5 g) was added to the solution, and the mixture was stirred at room temperature overnight. The reaction solution was filtered through Celite, and the solvent was removed from the filtrate by distillation under the reduced pressure to give (4,5-dimethylfuran-2-yl)(4,5-dimethylthiazol-2-yl)-methanone (910 mg, yield 97%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07560558B2
Source datasetuspto-grants-2009_07
ORD IDord-ff9c0126c13c495080a3055c9946dee9
Source noteuspto-grants-2009_07