TBAF tetrahydrofuran → HCID 56622945, compound

Participants

Reaction Steps

21 mg of compound (30) was mixed with 53.2 μl of 1M tetrabutylammonium fluoride-tetrahydrofuran solution, and the reaction was conducted at room temperature under stirring for 2 hours. The reaction solution was charged onto a silica gel column (Kieselgel 60, Merck, 1.0φ×30 cm) and eluted with n-hexane-ethyl acetate (2:1). The fraction containing the desired product was concentrated to dryness to give 16 mg of compound (31).

Provenance & Evidence