TBAF tetrahydrofuran → HCID 56637837, compound

Participants

Reaction Steps

13 mg of compound (33) was mixed with 200 μl of tetrahydrofuran and 14.8 μl of 1M tetrabutylammonium fluoride-tetrahydrofuran solution, and the reaction was conducted at room temperature under stirring for 15 hours. The reaction solution was charged onto a silica gel column (Kieselgel 60, Merck, 1.0φ×30 cm) and eluted with n-hexane-ethyl acetate (2:1). The fraction containing the desired product was concentrated to dryness to give 9.0 mg of compound (34).

Provenance & Evidence