TBAF tetrahydrofuran → HCID 15459992, compound

Participants

Reaction Steps

20 mg of compound (36) was stirred together with 242 μl of dry tetrahydrofuran and 36 μl of 1M tetrabutylammonium fluoride-tetrahydrofuran solution at room temperature for 1 hour. The reaction solution was concentrated in vacuo to give the crude reaction product. It was charged onto a silica gel column (Kieselgel 60, Merck, 1.5φ×15 cm) and eluted with n-hexane-ethyl acetate (3:1) to give 20.5 mg of compound (37) as a colorless oily substance.

Provenance & Evidence