TBAF tetrahydrofuran → HCID 15459996, compound

Participants

Reaction Steps

31 mg of compound (42) was stirred together with 1.23 ml of dry tetrahydrofuran and 55.3 μl of 1M tetrabutylammonium fluoride-tetrahydrofuran solution at room temperature for 3 hours. The reaction solution was concentrated in vacuo to give the crude reaction product. It was charged onto a silica gel column (Kieselgel 60, Merck, 1.0φ×20 cm) and eluted with n-hexane-ethyl acetate (4:1) to give 31.7 mg of compound (43) as a colorless oily substance.

Provenance & Evidence