TBAF tetrahydrofuran → HCID 56607385, compound

Participants

Reaction Steps

43.3 mg of compound (51) was stirred together with 435 μl of dry tetrahydrofuran and 65.3 μl of 1M tetrabutylammonium fluoride-tetrahydrofuran solution at room temperature for 1 hour. The reaction solution was concentrated in vacuo to give the crude product. The reaction product was charged onto a silica gel column (Kieselgel 60, Merck, 1.0φ×20 cm) and eluted with n-hexane-ethyl acetate (8:1) to give 22.5 mg of compound (52) as a colorless oily substance.

Provenance & Evidence