HCID 56607385, compound → HCID 18703955, compound

Participants

Reaction Steps

25.0 mg of compound (52) was dissolved in 2.89 ml of ethyl acetate and allowed to react in the presence of a catalytic amount of 10% palladium-carbon under stirring under a hydrogen atmosphere at room temperature for 1 hour. The reaction solution was filtered, and the filtrate was concentrated in vacuo. The reaction product was charged onto a silica gel column (Kieselgel 60, Merck, 1.0φ×21 cm) and eluted with n-hexane-chloroform (2:1) to give 12.3 mg of compound (53) as a colorless oily substance.

Provenance & Evidence