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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2288345Generated: November 1, 2026

Sodium Hydroxide → 2-[N-(4-amidinophenyl)aminomethyl]benzothiazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(hydroxycarbonylmethyl) amide dihydrochloride

https://huagongshe.com/reaction/2288345

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant2-[N-(4-amidinophenyl)aminomethyl]benzothiazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(ethoxycarbonylmethyl)amide dihydrochlorideHCID 18412445—
Product2-[N-(4-amidinophenyl)aminomethyl]benzothiazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(hydroxycarbonylmethyl) amide dihydrochlorideHCID 1841271790%

Reaction Steps

Prepared analogously to Example 10 from 2-[N-(4-amidinophenyl)-aminomethyl]-benzothiazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(ethoxycarbonylmethyl)-amide-dihydrochloride and sodium hydroxide solution. Yield: 90% of theory, C23H20N6O3S (460.52) Rf value: ##EQU1##

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06087380
Source datasetuspto-grants-2000_07
ORD IDord-9a277c8ef9684123a8c05bcd76e3c4e9
Source noteuspto-grants-2000_07