HRID2288354

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14798

Sodium Hydroxide

HNaO

结构：CCOC(=O)CCN(C(=O)c1ccc2sc(CCc3ccc(C(=N)N)cc3)nc2c1)c1ccccc1.Cl

HCID18412510

未命名化合物

PRODUCTS

生成物

结构：Cl.N=C(N)c1ccc(CCc2nc3cc(C(=O)N(CCC(=O)O)c4ccccc4)ccc3s2)cc1

HCID18412460

未命名化合物

收率 77%

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID176

Acetic Acid

C2H4O2

溶剂HCID21584144

Dichloromethane ethanol

C3H8Cl2O

PROCEDURE

实验过程

Prepared analogously to Example 10 from 2-[2-(4-amidinophenyl)ethyl]-benzothiazol-5-yl-carboxylic acid-N-phenyl-N-(2-ethoxycarbonylethyl)-amide-hydrochloride and sodium hydroxide solution. Yield: 77% of theory, C26H24N4O3S (472.57) Rf value: 0.18 (silica gel; methylene chloride/ethanol=4:1+a few drops of acetic acid) ##EQU5##