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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2288381Generated: November 1, 2026

Sodium Hydroxide → 1-Methyl-2-[(4-amidinophenyl)oxymethyl]benzimidazol-5-yl-carboxylic acid-N-phenyl-N-(hydroxycarbonylmethyl)amide Hydrochloride

https://huagongshe.com/reaction/2288381

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 18412425HCID 18412425—
Product1-Methyl-2-[(4-amidinophenyl)oxymethyl]benzimidazol-5-yl-carboxylic acid-N-phenyl-N-(hydroxycarbonylmethyl)amide HydrochlorideHCID 1841234958%

Reaction Steps

Prepared analogously to Example 26 from 1-methyl-2-[(4-amidinophenyl)oxymethyl]-benzimidazol-5-yl-carboxylic acid-N-phenyl-N-(ethoxycarbonylmethyl)-amide-hydrochloride and sodium hydroxide solution. Yield: 58% of theory, C25H23N5O4 (457.5) ##EQU22##

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06087380
Source datasetuspto-grants-2000_07
ORD IDord-36c2c0f26dbe4abb9169cbdbe97746b1
Source noteuspto-grants-2000_07