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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2288417Generated: October 26, 2026

Sodium Hydroxide → 1-Methyl-2-[N-(4-amidinophenyl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-cyclopentyl-N-(2-hydroxycarbonylethyl)amide

https://huagongshe.com/reaction/2288417

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant1-Methyl-2-[N-(4-amidinophenyl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-cyclopentyl-N-(2-ethoxycarbonylethyl)amide HydrochlorideHCID 18412350—
Product1-Methyl-2-[N-(4-amidinophenyl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-cyclopentyl-N-(2-hydroxycarbonylethyl)amideHCID 1841258345%

Reaction Steps

Prepared analogously to Example 26 from 1-methyl-2-[N-(4-amidinophenyl)-aminomethyl]-benzimidazol-5-yl-carboxylic acid-N-cyclopentyl-N-(2-ethoxycarbonylethyl)-amide-hydrochloride and sodium hydroxide solution. Yield: 45% of theory, C25H30N3O4 (462.6) ##EQU48##

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06087380
Source datasetuspto-grants-2000_07
ORD IDord-8b91b282114b47f6b9d7f3472c113823
Source noteuspto-grants-2000_07