HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 18412700, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Ammonium Carbonate | HCID 517111 | — |
| Reactant | HCID 18412407 | HCID 18412407 | — |
| Solvent | Dichloromethane ethanol | HCID 21584144 | — |
| Product | HCID 18412700 | HCID 18412700 | 86% |
Reaction Steps
Prepared analogously to Example 25d from 1-methyl-2-[N-(4-cyanophenyl)-aminomethyl]-benzimidazol-5-yl-carboxylic acid-N-(3-pyridyl)-N-(2-ethoxycarbonylethyl)-amide and ethanolic hydrochloric acid, ethanol and ammonium carbonate. Yield: 86% of theory, C27H29N7O3 (499.6) Rf value: 0.09 (silica gel; dichloromethane/ethanol=4:1 EKA mass spectrum: (M+H)+ =500
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06087380 |
| Source dataset | uspto-grants-2000_07 |
| ORD ID | ord-6ddd8934f15a427bb41bae788cdf8a2e |
| Source note | uspto-grants-2000_07 |