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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2288429Generated: November 1, 2026

Hydrochloric Acid → HCID 18412542, compound

https://huagongshe.com/reaction/2288429

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantEthanolHCID 702—
ReactantAmmonium CarbonateHCID 517111—
ReactantHCID 18412527HCID 18412527—
SolventDichloromethane ethanolHCID 21584144—
ProductHCID 18412542HCID 1841254288%

Reaction Steps

Prepared analogously to Example 25d from 1-methyl-2-[N-(4-cyanophenyl)-aminomethyl]-benzimidazol-5-yl-carboxylic acid-N-(2-fluorophenyl)-N-(2-ethoxycarbonylethyl)-amide and ethanolic hydrochloric acid, ethanol and ammonium carbonate. Yield: 88% of theory, C28H29FN6O3 (516.6) Rf value: 0.08 (silica gel; dichloromethane/ethanol=4:1) ##EQU57##

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06087380
Source datasetuspto-grants-2000_07
ORD IDord-9cff8ff296ad47d8b14a7eeb42108838
Source noteuspto-grants-2000_07