HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-Methyl-2-[-(4-amidinophenvl)aminomethyl]benzimidazol-5-yl-tert-butyl Ketone Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ammonium Carbonate | HCID 517111 | — |
| Reactant | 1-methyl-2-[N-(4-cyanophenyl)aminomethyl]benzimidazol-5-yl-tert-butyl ketone | HCID 18474037 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-Methyl-2-[-(4-amidinophenvl)aminomethyl]benzimidazol-5-yl-tert-butyl Ketone Hydrochloride | HCID 18474046 | 59% |
Reaction Steps
Prepared analogously to Example 25d from 1-methyl-2-[N-(4-cyanophenyl)-aminomethyl]-benzimidazol-5-yl-tert.butyl-ketone, ethanolic hydrochloric acid, ethanol and ammonium carbonate. Yield: 59% of theory, C21H25N5O (363.5) EKA mass spectrum: (M+H)+ =364
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06087380 |
| Source dataset | uspto-grants-2000_07 |
| ORD ID | ord-5631e63df9a7484db04ca62de5e6b34e |
| Source note | uspto-grants-2000_07 |