HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-Methyl-2-[N-(4-amidinophenyl)aminomethyl]benzimidazol-5-yl-(1-methylcyclopent-1-yl) ketone hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ammonium Carbonate | HCID 517111 | — |
| Reactant | 1-methyl-2-[N-(4-cyanophenyl)aminomethyl]benzimidazol-5-yl-(1-methylcyclopent-1-yl)ketone | HCID 69893555 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-Methyl-2-[N-(4-amidinophenyl)aminomethyl]benzimidazol-5-yl-(1-methylcyclopent-1-yl) ketone hydrochloride | HCID 69893700 | 63.5% |
Reaction Steps
Prepared analogously to Example 25d from 1-methyl-2-[N-(4-cyanophenyl)-aminomethyl]-benzimidazol-5-yl-(1-methylcyclopent-1-yl)-ketone, ethanolic hydrochloric acid, ethanol and ammonium carbonate. Yield: 63.5% of theory, C23H27N5O (389.5) EKA mass spectrum: (M+H)+ =390
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06087380 |
| Source dataset | uspto-grants-2000_07 |
| ORD ID | ord-10a064bc3c704955bdd28039e600133b |
| Source note | uspto-grants-2000_07 |