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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2288484Generated: October 30, 2026

Nicotinoyl chloride → HCID 140409608, compound

https://huagongshe.com/reaction/2288484

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNicotinoyl chlorideHCID 82604—
Reactant1-methyl-2-[2-(4-amidinophenyl)ethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide hydrochlorideHCID 18412669—
SolventDichloromethane methanolHCID 21226129—
ProductHCID 140409608HCID 14040960856%

Reaction Steps

Prepared analogously to Example 90 from 1-methyl-2-[2-(4-amidinophenyl)ethyl]-benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)-amide-hydrochloride and nicotinic acid chloride. Yield: 56% of theory, C34H33N7O4 (603.7) Rf value: 0.52 (silica gel; dichloromethane/methanol=9:1) ##EQU97##

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06087380
Source datasetuspto-grants-2000_07
ORD IDord-966d366399614ab8a69ff288a379e0b6
Source noteuspto-grants-2000_07