HRID2288505

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14798

Sodium Hydroxide

HNaO

结构：CCOC(=O)CCN(c1cnn(C)c1)S(=O)(=O)c1ccc2c(c1)nc(CNc1ccc(C(=N)N)cc1)n2C.Cl

HCID18412489

未命名化合物

PRODUCTS

生成物

结构：Cn1cc(N(CCC(=O)O)S(=O)(=O)c2ccc3c(c2)nc(CNc2ccc(C(=N)N)cc2)n3C)cn1

HCID18412535

未命名化合物

收率 95%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

Prepared analogously to Example 26 from 1-methyl-2-[N-(4-amidinophenyl)-aminomethyl]-benzimidazol-5-yl-sulphonic acid-N-(1-methylpyrazol-4-yl)-N-(2-ethoxycarbonylethyl)-amide-hydrochloride and sodium hydroxide solution. Yield: 95% of theory, C23H26N8O4S (510.6) Rf value: 0.53 (Reversed Phase silica gel RP-18, methanol+5% saline solution) ##EQU113##