HRID2288519

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14798

Sodium Hydroxide

HNaO

结构：CCOC(=O)CCN(C(=O)c1cc2c(nc(CNc3ccc(C(=N)N)cc3)n2C)s1)c1ccccc1.Cl

HCID18412312

未命名化合物

PRODUCTS

生成物

结构：Cl.Cn1c(CNc2ccc(C(=N)N)cc2)nc2sc(C(=O)N(CCC(=O)O)c3ccccc3)cc21

HCID18412621

未命名化合物

收率 85%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

Prepared analogously to Example 2 from 1-methyl-2-[N-(4-amidinophenyl)aminomethyl]-thieno[2.3-d]imidazol-5-yl-carboxylic acid-N-phenyl-N-(2-ethoxycarbonylethyl)-amide-hydrochloride and sodium hydroxide solution. Yield: 85% of theory, C24H24N6O3S (476.56) Rf value: 0.36 (Reversed Phase silica gel RP-8; methanol+5% saline solution) ##EQU117##