HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 18412540, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Ammonium Carbonate | HCID 517111 | — |
| Reactant | HCID 18412713 | HCID 18412713 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 18412540 | HCID 18412540 | 90% |
Reaction Steps
Prepared analogously to Example 25d from 1-methyl-2-[N-(4-cyanophenyl)-aminomethyl]-benzimidazol-5-yl-carboxylic acid-N-(4-fluorophenyl)-N-(2-ethoxycarbonylethyl)-amide and ethanolic hydrochloric acid, ethanol and ammonium carbonate. Yield: 90% of theory, C28H29FN6O3 (516.6) Rf value: 0.29 (silica gel; dichloromethane/methanol=5:1) ##EQU126##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06087380 |
| Source dataset | uspto-grants-2000_07 |
| ORD ID | ord-a5fc98a6bf5d428ca53c80143f7d11f6 |
| Source note | uspto-grants-2000_07 |