Ammonium Chloride → HCID 69965558, compound

Participants

Reaction Steps

Ammonium chloride (10 g) and 10 g of zinc were added to an Ar-purged suspension of 1.0 g of the ester from step (b) in ethanol. The mixture was stirred for 2 h, filtered and the solids washed with CH2Cl2. The combined solutions were evaporated to dryness producing a white solid which was dissolved in ethyl acetate and washed with 3×25 mL of water. The product was purified by chromatography using 10% ethyl acetate/hexane. 1H NMR (CDCl3) δ 5.48 (s, 1H), 5.69-7.27 (m, 9H), 7.41-7.55 (m, 5H), 7.83-7.88 (m, 2H).

Provenance & Evidence