Methyl triflate → HCID 18006796, compound

Participants

Reaction Steps

Naphthyl acridine-9-thiocarboxylate (26.38 g) was suspended in CH2Cl2 (200 mL). Methyl trifluoromethanesulfonate (24.5 ml) was added and the mixture left to stir overnight. The mixture was filtered and the solids washed with CH2Cl2 (300 ml) and hexanes (500 ml). After air drying, the product (28.83 g) was obtained as a yellow solid. 1H NMR (acetone-d6) δ 5.20 (s, 3H), 7.66-7.75 (m, 2H), 7.88-7.92 (m, 1H), 8.03-8.09 (m, 2H), 8.15 (d, 1H), 8.26 (t, 2H), 8.48 (s, 1H), 8.61-8.68 (m, 2H), 8.80 (d, 2H), 9.03 (d, 2H).

Provenance & Evidence