HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexane → 6-methoxy-7-methyl-1H-quinolin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexane | HCID 8058 | — |
| Reactant | 6-Methoxy-7-methyl-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid | HCID 12369036 | — |
| Solvent | Diphenyl Ether | HCID 7583 | — |
| Product | 6-methoxy-7-methyl-1H-quinolin-4-one | HCID 23078426 | 93% |
Reaction Steps
6-Methoxy-7-methyl-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid (22 g) was suspended in diphenyl ether (200 ml), and the suspension was heated under reflux overnight. The reaction solution was cooled to room temperature, hexane was then added to the reaction solution, and the precipitated crystal was collected by filtration to give 6-methoxy-7-methyl-1H-quinolin-4-one (16.6 g, yield 93%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07560558B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-4b02311bff3f49bdbaa1d772b7cd53d7 |
| Source note | uspto-grants-2009_07 |