HCID 53635885, compound → HCID 53799792, compound

HRID 2288770Notes

Reaction equation

HRID 2288770 reaction equation
[F:1]C1C=C(N2C[C@H](CNC(=O)C)OC2=O)C=CC=1N1C[C@@H]2[C@@H](CN(CCO)C2)C1.[F:30][C:31]1[CH:32]=[C:33]([N:49]2[CH2:53][C@H:52]([CH2:54][NH:55][C:56](=[O:58])[CH3:57])[O:51][C:50]2=[O:59])[CH:34]=[CH:35][C:36]=1[N:37]1[CH2:44][C@@H:43]2[C@@H:39]([CH2:40][N:41]([CH2:45][CH2:46]OC)[CH2:42]2)[CH2:38]1.FC1C=C(N2C[C@H](CNC(=O)C)OC2=O)C=CC=1N1C[C@@H]2[C@@H](CN(CC#N)C2)C1.FC1C=C(N2C[C@H](CNC(=O)C)OC2=O)C=CC=1N1C[C@@H]2[C@@H](CN(C(OC)=O)C2)C1>>[F:30][C:31]1[CH:32]=[C:33]([N:49]2[CH2:53][C@H:52]([CH2:54][NH:55][C:56](=[O:58])[CH3:57])[O:51][C:50]2=[O:59])[CH:34]=[CH:35][C:36]=1[N:37]1[CH2:44][C@@H:43]2[C@@H:39]([CH2:40][N:41]([CH2:45][CH2:46][F:1])[CH2:42]2)[CH2:38]1

Participants

5

Reactant 4

HCID 53635885HCID 53635885, compoundHCID 53886223HCID 53886223, compoundHCID 54312056HCID 54312056, compoundHCID 54526613HCID 54526613, compound

Product 1

HCID 53799792HCID 53799792, compound

Procedure

(S)-N-[[3-[3-fluoro-4-[cis-3-(2-hydroxyethyl)-3,7-diazabicyclo[3.3.0]octan-7-yl]phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide; (S)-N-[[3-[3-fluoro-4-[cis-3-(2-methoxyethyl)-3,7-diazabicyclo[3.3.0]octan-7-yl]phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide; (S)-N-[[3-[3-fluoro4-[cis-3-(cyanomethyl)-3,7-diazabicyclo[3.3.0]octan-7-yl]phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide; (S)-N-[[3-[3-fluoro4-[cis-3-(carbomethoxy)-3,7-diazabicyclo[3.3.0]octan-7-yl]phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide;

Sources & evidence

ORD record
ord-c0ef5e29afc54e5b9c09be196c951f9d
Source dataset
uspto-grants-2000_07
Patent number
US06090820

Reaction notes

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