Ethanethiol → HCID 15550460, compound

HRID 2288909Notes

Reaction equation

HRID 2288909 reaction equation
C[O:2][C:3]1[CH:4]=[CH:5][C:6]2[C:10]([C:11]([C:13]3[CH:18]=[CH:17][C:16]([O:19][CH2:20][CH2:21][O:22][CH2:23][CH3:24])=[CH:15][CH:14]=3)=[O:12])=[C:9]([C:25]3[CH:30]=[CH:29][C:28]([O:31]C)=[CH:27][CH:26]=3)[S:8][C:7]=2[CH:33]=1.C(S)C.[Cl-].[Al+3].[Cl-].[Cl-]>>[OH:2][C:3]1[CH:4]=[CH:5][C:6]2[C:10]([C:11]([C:13]3[CH:14]=[CH:15][C:16]([O:19][CH2:20][CH2:21][O:22][CH2:23][CH3:24])=[CH:17][CH:18]=3)=[O:12])=[C:9]([C:25]3[CH:26]=[CH:27][C:28]([OH:31])=[CH:29][CH:30]=3)[S:8][C:7]=2[CH:33]=1

Participants

4

Reactant 3

HCID 6343EthanethiolHCID 6451240Aluminum(III) ChlorideHCID 15550459HCID 15550459, compound

Product 1

HCID 15550460HCID 15550460, compoundYield 726.8%

Procedure

[6-Methoxy-2-(4-methoxyphenyl)benzo[b]thiophen-3-yl][4-(ethoxyethoxy)phenyl]methanone (0.35 g, 0.76 mmol) was converted to 2.4 g of the title compound by the procedure of Example 3 using 0.28 mL (3.79 mmol) of ethanethiol and 0.61 g (4.6 mmol) of aluminum chloride.

Sources & evidence

ORD record
ord-10664a6e70564aeabff2cbe934285f39
Source dataset
uspto-grants-2000_07
Patent number
US06090843

Reaction notes

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